EMMAA Model Queries

The Queries page can be accessed by clicking the “Queries” link at the top of the Dashboard website.

Submitting a Query

The model queries page can answer direct queries about one or more models. A query consists of a statement type, a subject, and an object. Together with the query, at least one model needs to be selected for the query submission to be valid.

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The query ready to be submitted that asks if BRAF activates ERK in the AML and BRCA cancer models.

If the query is badly formatted or missing information, an error will be shown stating the type of error.

The query will be received by the query service and return a response which is displayed in the Results table below. The result for each model is either a mechanistic path reported in English language which satisfies the query condition, or an explanation of why the query could not be evaluated on the model.

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The above query resolved, showing the result per model and model type. If a path was found, the path is shown, otherwise the reason why a path was not found is is stated.

The page displays “Waiting for server response” and a loader bar while the query is being executed. The typical response time can be up to a minute so please be patient when posting queries.

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While the query resolves, a small animation is shown.

Logging In and Registering a User

A user can log in by clicking the “Login” button to the right on the navigation bar. When clicking the login button, an overlay shows up asking for credentials. A user can also create an account by clicking “Register” if they don’t already have an account.

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The login and registration tabs of the login overlay.

Subscribing to a Query

When logged in, a user can register a query for subscription. To register a subscription to a query, the tick box for “Subscribe To Query” has to be ticked when the query is submitted. After submission, the query is associated with the logged in user. When returning to the page, the subscribed queries will be loaded together with their latest results.

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The table for subscribed queries, here for the query Activation(FLT3, KRAS) of the AML cancer model.